In the Indiana Jones series Edit
The Ark of the Covenant plays a key role in the first Indiana Jones film Raiders of the Lost Ark.
It appears on the wall as a carving in the underground Venice sewer in the Last Crusade
It appears in the Kingdom of the Crystal Skull when it's crate is smashed open in Hangar 51.
In Lego Indiana JonesEdit
The Ark of the Covenant is included in one LEGO set: The Lost Tomb.
In Lego Indiana Jones Games Edit
It appears in The Original Adventures (Opening the Ark) and The Adventure Continues (Belloq Battle). It also appears in the level Hangar Havoc in the Adventure Continues. If you go past the first gate, there's a ladder. Go up the ladder and at the top you'll be able to see it. Things will float around it before it suddenly explodes.